Non-deletion haemoglobin H disease in Papua New Guinea.
نویسندگان
چکیده
Analysis of DNA from members of a Melanesian family from Papua New Guinea with haemoglobin (Hb) H disease revealed that all four alpha globin genes are intact in affected subjects. Study of restriction enzyme site and length polymorphisms and the use of oligonucleotide probes indicated that the molecular basis of this Papuan form of non-deletion Hb H disease differs from the previously described Middle Eastern and Mediterranean types.
منابع مشابه
Methicillin-Resistant Staphylococcus Aureus in Melanesian Children with Haematogenous Osteomyelitis from the Central Highlands of Papua New Guinea
Background: Methicillin-Resistant Staphylococcus aureus (MRSA) has been an important cause of bone infection since the 1940s. Current guidelines recommend targeted antibiotic use for osteomyelitis treatment informed by microbial sensitivity patterns. However, in settings without microbiology facilities, empirical antibiotic use is common. Unrecognized antibiotic resistance potentiates persisten...
متن کاملGlobal Health Diplomacy, National Integration, and Regional Development through the Monitoring and Evaluation of HIV/AIDS Programs in Papua New Guinea, Vanuatu, and Samoa
The South Pacific countries of Vanuatu, Samoa, and Papua New Guinea have ascended rapidly up the development spectrum in recent years, refining an independent and post-colonial economic and political identity that enhances their recognition on the world stage. All three countries have overcome economic, political and public health challenges in order to stake their claim to sovereignty. In this...
متن کاملA Partnership Model for Improving Service Delivery in Remote Papua New Guinea: A Mixed Methods Evaluation
Background The Community Mine Continuation Agreement Middle (CMCA) and South Fly Health Program (the Health Program) is a partnership for improving health service delivery in remote Papua New Guinea (PNG). The Health Program is delivered by a private contractor working in partnership with existing health service providers to improve service delivery using existing government systems, where poss...
متن کاملCauses of preterm delivery and intrauterine growth retardation in a malaria endemic region of Papua New Guinea.
AIM To identify causes of preterm delivery and intrauterine growth retardation (IUGR) in a malaria endemic region of Papua New Guinea. METHODS Independent predictors of preterm delivery and birthweight in term infants were identified using multiple regression analysis in a prospective study of 987 singleton live births delivered in Madang Hospital. RESULTS Overall, Plasmodium falciparum inf...
متن کاملA survey of diabetes services in hospitals in Papua New Guinea.
AIM To determine the number and distribution of diabetic persons in Papua New Guinea (PNG), and to document available services. METHODS Survey of the 19 hospitals thought to be the most significant centres for care of diabetes. RESULTS 16 hospitals were successfully surveyed. Type 1 diabetes is very rare, with 18 known cases in the country (6 less than 15 years old). Known type 2 cases tota...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of medical genetics
دوره 24 12 شماره
صفحات -
تاریخ انتشار 1987